3.4 Million

Dialysis patient
worldwide

  • [1,3]

Diabetes and high blood pressure are the most prevalent causes of kidney disease. Patients with end stage kidney disease require their blood to be routinely filtered externally through haemodialysis.

Globally, the number of patients with kidney failure grows by 6% annually, resulting in an estimated 4.9 million patients in 2025.

Pathfinder line sail  repeat pattern

Vascular Access Creation

For the last 50 years, open surgery has been the current gold standard for preparing patients for dialysis. This involves suturing together an artery and vein in the forearm to create a vascular access site (Arteriovenous Fistula or AVF) for the dialysis machine to connect to.

640,000

surgical AVF creations per year

  • [2,3]

Surgical AVF Outcomes

An AVF is a patient's lifeline and is crucial to receiving dialysis treatment. High failure rates of surgical AVFs result in multiple repeat salvage procedures.

25%

Surgical
Failure

50%

1 year
patient

3.43

Salvage Procedures

Per patient year

3-6

Months

Time to heal and mature

Cost of Failure

$5,000 to $15,000

per salvage procedure

$4.6
Billion

US yearly spend on failing
dialysis access sites

The ePATH endoAVF system aims to reduce the burden on patients and healthcare systems through a more reliable alternative to surgical AVF creation.

Peripheral Arterial Disease

Diabetes is also a major cause of peripheral arterial disease.

A Chronic Total Occlusion (CTO) is the most severe stage of the disease and presents a serious risk of amputation due to the complete lack of blood flow.

194,000

amputations p.a. in the US and UK

22-30
Million

with most advanced
stage (CTO)

60%

Average
Re-entry
Success Rate

The ePATH Re-Entry catheter kit will provide clinicians with a safer, more precise, and more reliable approach to CTO True Lumen Re-entry procedures.

110,000

Peripheral CTO procedures globally p.a. (2020)

  • [20]